TB Alert: Papers and publications

Mon 23rd - tues 24th April 2012
Registration from 9:30 am on the 23rd
Department for continuing Education,
Rewley House,
Oxford
Applications being accepted

The two-day Clinical Vaccine Development module can be taken either as a stand-alone module or can be taken as an add-on to the Human and Veterinary Vaccinology module. The course will be designed in close collaboration with clinicians, veterinarians and industrial partners who conduct clinical trials to provide:

• An overview of pre-clinical testing and the pathway from pre-clinical testing to field trials.
• A more detailed discussion of vaccine immunogenicity, testing vaccine immunogenicity in the field and the need for correlates of immune protection. The different phases of vaccine testing from Phase I to IV.
• An overview of the development of veterinary vaccines.
• An introduction to the principles and conduct of Good Clinical Practice.

Read more and apply here

id: 24/01/11Oxford

(24/01/11) University of Oxford: Vaccine Biomanufacturing

Weds 25th- thurs 26th April 2012
Registration at 09:00 am on the 25th
Department for continuing Education,
Rewley House,
Oxford
Applications being accepted

The two-day Vaccine Biomanufacturing module can be taken either as a stand-alone module or can be taken as an add-on to the Human and Veterinary Vaccinology module. The course will be designed in close collaboration with our industrial partners to provide:

• An overview of vaccine markets and growth drives for developed and developing settings.
• An overview of the biomanufacturing processes used for the production of a spectrum of vaccines.
• The principles of GMP (Good Manufacturing Practice) and how these are applied to vaccine production.
• An introduction to Quality Assurance and the use of molecular methods to verify quality.

Read more and apply here

id: 24/01/11Oxford

(24/01/11) University of Oxford: Immunology: A Pathway through the Maze

Weds 16th - thurs 17th May 2012
Registration at 10:30 am on the 16th
Department for continuing Education,
Ewert House,
Oxford
Applications being accepted

Immunology is a rapidly developing subject with wide-ranging implications for the pharmaceutical, healthcare and biotechnology industries. Common questions include, for example: How does the immune system defend the body against infection? What goes wrong when autoimmunity develops? How can undesirable responses be controlled? Team leaders, R&D directors, and researchers at the bench all need to understand the latest developments in immunology and their implications for drug discovery and development as well as disease treatment.

An understanding of the fundamental features of the immune system is essential not only for those who work in areas directly related to infection and immunity, but also for those working in the development of biopharmaceuticals, vaccines and antibody therapy, who wish to exploit the technological advances that have resulted from our increased insight into how the system functions.

Read more and apply here

id: 24/01/11Oxford

Human and Veterinary Vaccinology course

Mon 10th - fri 14th
Registration at 09:00 am on the 10th
Department for continuing Education,
Rewley House,
Oxford
Applications being accepted

The Human and Veterinary Vaccinology course is a five-day Master’s level course designed to stand alone and cover all aspects of vaccinology.

The course includes contributions from 18 world-leading experts, including:

• Prof David Salisbury (Director of Immunisation, UK Department of Health)
• Dr Mike Whelan (Head of R & D, iQur Ltd)
• Dr Vasee Moorthy (Department of Immunization, Vaccines & Biologicals, World Health Organisation)
• Prof Andrew Pollard (Director, Oxford Vaccine Group, University of Oxford)
• Dr Laura Martin (Development Project Leader, Novartis Vaccines Institute for Global Health)
• Prof Adrian Hill (Director, Jenner Institute, University of Oxford)

Read more and apply here

id: 24/01/11Oxford

Treatment interruptions and inconsistent supply of drugs in the UK

New research, published in the June 2011 edition of the The International Journal of Tuberculosis and Lung Disease (IJTLD), has found that NHS centres treating tuberculosis in the UK commonly experience difficulties in obtaining drugs to treat both drug-susceptible and drug-resistant TB.

63% of treatment centres reported difficulties in obtaining anti-tuberculosis drugs, leading 27% to interrupt the prescribed treatment regimen and 19% to alter the regimen. 36% of centres treating multi-drug resistant TB reported difficulties obtaining second-line drugs, 16% had to interrupt the prescribed treatment regimen at least once and 5% had to alter the regimen. A lack of licensed liquid formulations for children resulted in 26% of treatment centres using unlicensed, variable-strength liquids and locally prepared suspensions.

Non IJTLD subscribers can access and download the articles from Ingenta's "Pay-per-view" option here.
id: 31.05.11IJTLD

Scottish TB Action Plan launched

The TB Action Plan has been launched by the Scottish Government for use by professionals working to deliver TB related services in Scotland. This document details the recommendations of the TB Action Plan Working Group, which included representation from TB Alert on the clinical services sub-group.

The document covers:
Introduction and Background
Laboratory Services and Diagnostic Tools
Clinical Services
Surveillance
Public Health Services
Monitoring and Ensuring Progress
Membership of TB Action Plan Working Group
Membership of Subgroups
Summary of Recommendations

Download it here, or direct from the Scottish Government website.

id: 28.03.11STBAP

(18/02/11) Sheffield University research: TB in the Somali Community

Tackling TB together: a community participatory study of the socio-cultural factors influencing an understanding of TB within the Somali community in Sheffield (2010): Kate Gerrish, Mubarak Ismail, Andy Naisby, Sheffield Hallam University. Download the report.
id: 18.02.11SomaliResearch

(11/01/11) TB and tobacco control: their role on the global health agenda, Thomas Frieden at the 41st Union World Conference Inaugural Session

The inaugural lecture at the 41st Union World Conference from the International Union Against Tuberculosis and Lung Disease, given by Thomas Frieden, Director of the Centre for Disease Control. Thom previously led New York’s successful strategy to control TB. The lecture, which focuses specifically on tobacco control, is framed around the life and work of TB Alert’s late President, Sir John Crofton, who was a huge influence on Dr Frieden. View it here...
id: 11.01.11IUATLD

(04/11/10) Tuberculosis in the UK: Annual report on tuberculosis surveillance in the UK 2010, Health Protection Agency

The Health Protection Agency's annual TB suveillance report, which shows that the trend of rising numbers of TB cases continued in 2009:

- 4.2% rise in cases compared with 2008

- 15 cases per 100,000 population in the UK

- 9,040 cases

- Concentration in urban centres

- 38% of cases in London, with a rate of 44.4 per 100,000

The full report can be downloaded from the HPA website.

id: 04/11/10HPATB2010

Update: 04/11/10

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